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Advancing research and collaboration in CCHFV preparedness. CCHFVACIM is driving forward cutting-edge research through a collaborative, multidisciplinary approach to pandemic preparedness. During the first phase of the project, important scientific advances have been achieved, including the characterization of key viral structures and immune responses, as well as the identification of promising vaccine targets. The project…

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CCHFVACIM Builds on EU Research to Advance a Vaccine Significant progress has been made in the global fight against Crimean-Congo Haemorrhagic Fever (CCHF) — a severe tick-borne viral disease with fatality rates that can reach 40 % and no licensed vaccine available. CCHF is transmitted to humans through the bite of infected Hyalomma ticks, and…

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CCHFVACIM reaches key milestones in its first reporting period. The CCHFVACIM project has made significant progress during its first reporting period (January 2024 – June 2025), laying strong foundations for the development of innovative vaccines and immunotherapies against Crimean-Congo Haemorrhagic Fever (CCHF). Among the key achievements, the consortium successfully designed and evaluated multiple mRNA-based vaccine…

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Our team developed a rapid, versatile “plug-and-play” pseudotyped virus neutralisation assay that allows scientists to measure immune responses to several dangerous bunyaviruses without needing high-containment (BSL-3/4) facilities.This is a major step forward because: 🔍 Why it matters for CCHFVACIMThe CCHFVACIM project aims to advance vaccines and medical countermeasures against CCHFV. One of our biggest bottlenecks…

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Greek health authorities have reported a confirmed case of Crimean-Congo hemorrhagic fever (CCHF) in a 71-year-old man. Initially presenting with fever, myalgia, and gastrointestinal symptoms, his condition evolved rapidly to include neurological signs and hemorrhages, leading to his death shortly after diagnosis. 🇬🇷 This is Greece’s first CCHF case in 2025 and only the second…

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CCHF Epidemic watch The Iraqi Ministry of Health has reported a growing number of cases and deaths linked to Crimean-Congo Hemorrhagic Fever (CCHF), signaling one of the country’s most significant outbreaks in recent years.As of late September 2025, 296 confirmed infections and 42 deaths have been recorded nationwide since the beginning of the year —…

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With the Scientific Watch series, CCHFVACIM brings you timely updates on research, outbreaks, and global health developments related to Crimean-Congo haemorrhagic fever (CCHF) and other high-consequence viruses. Our aim is to highlight scientific advances, surveillance findings, and policy-relevant insights that connect directly to the mission of CCHFVACIM: strengthening preparedness through better vaccines, therapeutics, and diagnostics.…

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Discover our new A4 brochure (two-sided) presenting the CCHFVACIM project, its mission, partners, and scientific ambition.It provides a clear overview of how the consortium is advancing vaccines and immunotherapies against Crimean-Congo haemorrhagic fever, through a One Health-driven, interdisciplinary approach. 👉 [Download the brochure here]

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Immunogenicity of NSDV GP38 and the Role of Furin in Glycoprotein Processing We are proud to highlight a new peer-reviewed publication by Kerstin Fischer and colleagues at the Friedrich-Loeffler-Institut (FLI), supported by the CCHFVacim project and funded by the European Health and Digital Executive Agency (HaDEA). 🔬 The study explores the presence and immunogenicity of the GP38 glycoprotein in sheep…

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For partners: Want to showcase CCHFVACIM activities? Download our A0 poster! If you’re looking for a clear, visual way to communicate about the CCHFVACIM project, our A0 poster is the perfect tool. Whether you’re attending a conference, meeting with partners, or simply want to raise awareness, this poster gives a concise and impactful overview of…

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